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Neuropsychopharmacology; Recovery of
Function/Neural Plasticity. My research program
emphasizes the relations between brain activity
and behavior, and is presently focused on the
functional organization of central monoamine
neurons. Ongoing studies concern: (1) the nature
of long-term changes in brain catecholamine
systems and behavior produced by repeated
exposure to psychomotor stimulant drugs or
stress, and the implications of these for addiction
and relapse; and (2) the nature of neural
adaptations responsible for recovery of function
following damage to brain monoamine systems.
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Robinson, T.E. and Berridge, K.C.: The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Research Reviews 18:247-291, 1993. Crombag, H., Badiani, A., Robinson, T.E.: Signalled versus unsignalled intravenous amphetamine: Large differences in the acute psychomotor response and sensitization. Brain Research 722:227-231, 1996. Badiani, A., Camp, D.M., Robinson, T.E.: Enduring enhancement of emphetamine sensitization by drug-associated environmental stimuli. J. Pharmacol. Exp. Ther. 28:787-794, 1997. Robinson, T.E. and Kolb, B.: Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by prior experience with amphetamine. Journal of Neuroscience 17:8491-8497, 1997. Robinson, T.E., Browman, K.E., Crombag, H.S.,
Badiani, A.: Modulation of the induction or
expression of psychostimulant sensitization by
the circumstances surrounding drug
administration. Neuroscience and Biobehavioral
Reviews 22:347-354, 1998.
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